Update: CBSsports.com is reporting that New England Patriots QB Tom Brady has been listed as questionable on the team's injury report for the team's game on Thanksgiving Day against the Detroit Lions. Brady missed practice Wednesday for the second straight day with foot and shoulder injuries. However, ESPN's John Clayton said that he expects Brady to play.

Fantasy Impact: Brady will most likely play through the pain, but that doesn't mean this injury isn't threatening his playing time. Keep a close eye on him up until gametime and keep him in fantasy starting lineups unless it has been determined that he won't play.

Update: CBSsports.com is reporting that New England Patriots QB Tom Brady has been listed as questionable on the team's injury report for the team's game on Thanksgiving Day against the Detroit Lions. Brady missed practice Wednesday for the second straight day with foot and shoulder injuries. However, ESPN's John Clayton said that he expects Brady to play.

Fantasy Impact: Brady will most likely play through the pain, but that doesn't mean this injury isn't threatening his playing time. Keep a close eye on him up until gametime and keep him in fantasy starting lineups unless it has been determined that he won't play.

Update: ESPN.com is reporting that the New Orleans Saints are optimistic that RB Reggie Bush will be able to play Thursday against the Dallas Cowboys. Bush has missed eight games due to a broken right leg and is listed as questionable after limited practice this week.

Fantasy Impact: The Saints have suffered in their run game in the absence of Bush and RB Pierre Thomas who are both hurt. Bush's presence on the field should open up the passing game and allow the Saints to get back to playing the way the did on their way to a Super Bowl victory last season. In terms of fantasy, keep a close eye on him and if heis going to start, consider him a number two back.

Update: ESPN.com is reporting that the New Orleans Saints are optimistic that RB Reggie Bush will be able to play Thursday against the Dallas Cowboys. Bush has missed eight games due to a broken right leg and is listed as questionable after limited practice this week.

Fantasy Impact: The Saints have suffered in their run game in the absence of Bush and RB Pierre Thomas who are both hurt. Bush's presence on the field should open up the passing game and allow the Saints to get back to playing the way the did on their way to a Super Bowl victory last season. In terms of fantasy, keep a close eye on him and if heis going to start, consider him a number two back.

Update: ESPN.com is reporting that Cleveland Browns QB Jake Delhomme will start ahead of injured QB Colt McCoy. McCoy is suffering from an ankle sprain and will not be able to play on Sunday. McCoy is the third Browns quarterback to go down with an ankle sprain this season.

Fantasy Impact: McCoy was shining as the Browns starter before going down with the ankle injury. Delhomme was the starter at the beginning of the season, however, so the performance at quarterback shouldn't change too drastically. Still, stay away from Delhomme in all fantasy leagues.

Update: ESPN.com is reporting that Washington Redskins RB Clinton Portis has been placed on injured reserve, ending his season. Portis re-aggravated a groin injury that kept him out several weeks, and it was severe enough to make Washington end his season early for the second straight year.

Fantasy Impact: This move may signal the end of Portis's career in Washington. The 29 year-old running back is only 77 rushing yards shy of 10,000 for his career. Obviously, drop him in all fantasy leagues.

Update: Giants head coach Tom Coughlin announced Wednesday that Brandon Jacobs will replace Ahmad Bradshaw as New York’s starting running back. The Newark Star-Ledger is reporting that Coughlin said: “The No.1 consideration is to try to stop beating ourselves. That’s one area we should be able to improve. It’s very frustrating not to improve in that area.” Bradshaw’s six fumbles this season, including a key one Sunday night in Philadelphia, were clearly the main factor in Coughlin’s decision. Bradshaw was not at all happy with the news to which Coughlin responded, “He’s going to fight his way through it. Why it would be a total surprise to anyone is beyond me.” As for the newly re-appointed starting running back, Jacobs, the head coach commented, “Brandon has been running the ball (well). It’s basically been almost like a 2-to-1 deal. Both guys have gotten lots of carries.”

Fantasy Impact: Turnovers have plagued the Giants throughout the year, and Coughlin made his growing lack of patience with the issue known before this past Sunday night’s game. With the five costly turnovers that wasted a stout defensive effort in Philadelphia en route to a second straight loss, a significant change was almost inevitable. Bradshaw has over 1,000 total yards this season and is averaging 4.7 yards per carry, but his propensity for coughing up the ball has deflated the team at the most crucial moments. The job was originally Jacobs’ before Bradshaw outperformed Jacobs in offseason workouts and preseason, so the starting job is by no means etched in stone to be Jacobs’. Bradshaw will still get a solid number of touches, so whichever back proves to be more dependable and capable of making Eli Manning and the coaching staff’s job easier will be the main guy in the Big Blue backfield.